Individual response to treatment: is it a valid assumption?

被引：110

作者：

Senn, S ^{[1
]}

机构：

[1] Univ Glasgow, Dept Stat, Glasgow G12 8QQ, Lanark, Scotland

来源：

BMJ-BRITISH MEDICAL JOURNAL | 2004年 / 329卷 / 7472期

关键词：

D O I：

10.1136/bmj.329.7472.966

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Most drug trials assume that patients respond consistently to treatment, but the assumption is rarely tested. If patients vary randomly in their response to a drug rather than some patients never responding, searches for a genetic basis for non-response are futile.

引用

页码：966 / +

页数：3

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