Synthesis of two novel cysteine-functionalized thiophenes

被引：5

作者：

Cagnoli, R

Lanzi, M

Mucci, A

Parenti, F

Schenetti, L

机构：

[1] Univ Modena, Dipartimento Chim, I-41100 Modena, Italy

[2] Univ Bologna, Dipartimento Chim Ind & Mat, I-40136 Bologna, Italy

来源：

SYNTHESIS-STUTTGART | 2005年 / 02期

关键词：

cysteine; thiophenes; sulfur heterocycles; serine; nucleophilic substitution;

D O I：

10.1055/s-2004-834930

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthetic approach to methyl N-(tert-butoxycarbonyl) -S- (3-thienyl)-L-cysteinate (1) and methyl N-(tert-butoxycarbonyl)-S-[2-(3-thienyl)ethyl]-L-eysteinate (2) through tosylate intermediates is reported and discussed. These compounds, which combine the properties of the cysteine side-chain with those of the thiophene ring represent both potential bioactive molecules and interesting synthons for the development of new materials.

引用

页码：267 / 271

页数：5

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[2]

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