Structure-activity relationship for quantifying aromatic interactions

被引：65

作者：

Carver, FJ

Hunter, CA ^{[1
]}

Seward, EM

机构：

[1] Univ Sheffield, Dept Chem, Krebs Inst Biomolec Res, Sheffield S3 7HF, S Yorkshire, England

[2] Merck Sharp & Dohme Ltd, Harlow CM20 2QR, Essex, England

来源：

CHEMICAL COMMUNICATIONS | 1998年 / 07期

关键词：

D O I：

10.1039/a800567b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The magnitudes of a range of intermolecular edge-to-face aromatic interactions are measured using chemical double mutant cycles in synthetic H-bonded molecular zipper complexes, and good correlations are obtained with the Hammett substituent constants, suggesting that the results can be extrapolated to other functional group combinations.

引用

收藏

页码：775 / 776

页数：2

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