Lipophosphoglycan (LPG) and the identification of virulence genes in the protozoan parasite Leishmania

被引：141

作者：

Beverley, SM ^{[1
]}

Turco, SJ

机构：

[1] Washington Univ, Sch Med, Dept Mol Microbiol, St Louis, MO 63110 USA

[2] Univ Kentucky, Dept Biochem, Lexington, KY 40536 USA

来源：

TRENDS IN MICROBIOLOGY | 1998年 / 6卷 / 01期

关键词：

D O I：

10.1016/S0966-842X(97)01180-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Leishmania exploits several strategies to survive within the phagolysosome of vertebrate macrophages and be transmitted by sand fly vectors. Recent advances in functional genetic analysis provide a new avenue for identifying genes implicated in the infectious cycle of the parasite, such as those necessary for the synthesis and expression of the key surface glycoconjugate, lipophosphoglycan (LPG).

引用

页码：35 / 40

页数：6

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