Association of inflammatory markers with angiographic severity and extent of coronary artery disease

被引：102

作者：

Drakopoulou, Maria ^{[1
]}

Toutouzas, Konstantinos ^{[1
]}

Stefanadi, Elli ^{[1
]}

Tsiamis, Eleftherios ^{[1
]}

Tousoulis, Dimitris ^{[1
]}

Stefanadis, Christodoulos ^{[1
]}

机构：

[1] Univ Athens, Sch Med, Dept Cardiol 1, Hippokrat Hosp, GR-11527 Athens, Greece

来源：

ATHEROSCLEROSIS | 2009年 / 206卷 / 02期

关键词：

C-reactive protein; Atherosclerosis; Inflammation; Coronary angiography; C-REACTIVE PROTEIN; ACUTE MYOCARDIAL-INFARCTION; OPTICAL COHERENCE TOMOGRAPHY; STABLE ANGINA-PECTORIS; ATHEROSCLEROTIC PLAQUES; UNSTABLE ANGINA; SMOOTH-MUSCLE; HEART-DISEASE; POSSIBLE LINK; ATHEROTHROMBOSIS;

D O I：

10.1016/j.atherosclerosis.2009.01.041

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Inflammatory processes play a pivotal role in the pathogenesis of atherosclerosis and mediate many of the stages of atheroma development, from initial leukocyte recruitment to eventual rupture of the unstable atherosclerotic plaque. Several systemic inflammatory markers reflect different degrees of inflammation and have been indicated as independent risk factors in cardiovascular disease, especially in unstable coronary syndromes. However, whether elevated levels of circulating inflammatory markers play a role in the extent and severity of atherosclerosis remains controversial. The present review summarizes our current understanding of the relationship between inflammatory markers and the presence and extent of coronary atherosclerosis, in order to assess the potential utility of these markers in identifying patients with higher levels of atherosclerotic burden. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

引用

页码：335 / 339

页数：5

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