Physicians' propensity to offer genetic testing for Alzheimer's disease: Results from a survey

被引：20

作者：

Chase, GA

Geller, G

Havstad, SL

Holtzman, NA

Bassett, SS

机构：

[1] Johns Hopkins Univ, Sch Med, Henry Ford Hlth Sci Ctr, Dept Biostat & Res Epidemiol, Baltimore, MD USA

[2] Johns Hopkins Univ, Sch Med, Bioeth Inst, Baltimore, MD USA

[3] Johns Hopkins Univ, Sch Med, Inst Med Genet, Baltimore, MD USA

[4] Johns Hopkins Univ, Sch Med, Dept Psychiat & Behav Sci, Baltimore, MD USA

来源：

GENETICS IN MEDICINE | 2002年 / 4卷 / 04期

关键词：

Alzheimer's disease; genetic testing; physician survey; genetics;

D O I：

10.1097/00125817-200207000-00008

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

dPurpose: Examine physician knowledge, preferences, and use of genetic tests for Alzheimer's disease (AD). Methods: Survey of 426 community-based physicians treating AD patients. Results: Majority gave inaccurate estimates of AD risk. Medical specialty predicted appropriate use of current tests. Recommending substances to prevent memory loss was related to acceptance of error-free tests. High patient loads and familiarity with genetic tests predicted lower tolerance for test error. Conclusion: Physicians do not endorse indiscriminate genetic susceptibility testing for AD. However, insufficient knowledge of disease risk, etiology, genetic susceptibility, and use of existing tests indicated a need for further physician education in this area.

引用

页码：297 / 303

页数：7

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