Levobupivacaine-induced seizures and cardiovascular collapse treated with Intralipid®

被引：156

作者：

Foxall, G. ^{[1
]}

McCahon, R. ^{[1
]}

Lamb, J. ^{[1
]}

Hardman, J. G. ^{[1
]}

Bedforth, N. M. ^{[1
]}

机构：

[1] Queens Med Ctr, Univ Dept Anaesthesia, Nottingham NG7 2UH, England

来源：

ANAESTHESIA | 2007年 / 62卷 / 05期

关键词：

D O I：

10.1111/j.1365-2044.2007.05065.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Lipid emulsion has been used in the successful treatment of local anaesthetic-induced cardiovascular collapse in animals and in two cases of cardiac arrest in humans. Previous reports of levobupivacaine toxicity in humans have been characterised by neurological signs and symptoms, without serious cardiovascular events. We present a case in which presumed intravenous injection of levobupivacaine led to neurological and cardiovascular consequences. This was treated successfully by resuscitation that included intravenous Intralipid((R)) infusion.

引用

页码：516 / 518

页数：3

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