Phyto-oestrogens through the life cycle

被引:38
作者
Cassidy, A [1 ]
Faughnan, M [1 ]
机构
[1] Univ Surrey, Sch Biol Sci, Ctr Nutr & Food Safety, Guildford GU2 5XH, Surrey, England
关键词
phyto-oestrogens; isoflavones; lignans; soyabean;
D O I
10.1017/S0029665100000719
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The growing interest in the role of phyto-oestrogens in human health has prompted scientists to evaluate the risk:benefit which would result from consuming high levels of these compounds at different stages of the life cycle. These compounds have been shown to exert a wide range of hormonal and non-hormonal activities in animals and in vitro, and these activities suggest plausible mechanisms for potential health effects in human subjects consuming phyto-oestrogen-rich diets. In addition, experimental and epidemiological data are available supporting the concept that phyto-oestrogen-rich diets exert physiological effects in vivo; however, their relative importance to human health remains to be elucidated. Our understanding of factors involved in their absorption and metabolism, including the role of intestinal microflora, is limited, and these factors together with dose-related effects may well be important in determining clinical efficacy.
引用
收藏
页码:489 / 496
页数:8
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