The brain's own marijuana

被引:21
作者
Nicoll, RA [1 ]
Alger, BE [1 ]
机构
[1] Univ Maryland, Sch Med, Baltimore, MD 21201 USA
关键词
D O I
10.1038/scientificamerican1204-68
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The investigation of endocannabinoids leading to discovery of a new signalling system in the brain, depolarization-induced suppression of inhibition (DSI), for treatment related to brain and other medical problems is discussed. DSI, enables individual neurons to disconnect briefly from their neighbors and encode information. The results indicate that endocannabinoids are important in extinguishing the bad feelings and pain triggered by reminders of past experiences. It is suggested that abnormally low numbers of cannabinoid receptors are involved in post-traumatic stress syndrome, phobias and certain forms of chronic pains.
引用
收藏
页码:68 / 75
页数:8
相关论文
共 3 条
[1]  
Alger BE, 2002, PROG NEUROBIOL, V68, P247
[2]  
Joy J.E., 1999, MARIJUANA MED
[3]   Neuroscience - Endocannabinoid signaling in the brain [J].
Wilson, RI ;
Nicoll, RA .
SCIENCE, 2002, 296 (5568) :678-682