Absolute configuration of norzoanthamine, a promising candidate for an osteoporotic drug

被引：50

作者：

Kuramoto, M

Hayashi, K

Fujitani, Y

Yamaguchi, K

Tsuji, T

Yamada, K

Ijuin, Y

Uemura, D

机构：

[1] SAGAMI CHEM RES CTR, SAGAMIHARA, KANAGAWA 229, JAPAN

[2] SHIZUOKA UNIV, FAC SCI, DEPT CHEM, SHIZUOKA 422, JAPAN

[3] EHIME UNIV, ADV INSTRUMENTAT CTR CHEM ANAL, MATSUYAMA, EHIME 79077, JAPAN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 32期

关键词：

D O I：

10.1016/S0040-4039(97)01238-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The absolute configuration of norzoanthamine (1) was determined to be 2R, 4S, 6S, 9S, 10R, 12R, 13R, 18S, 21S, and 22S based on H-1 NMR spectral data of the MTPA esters of norzoanthamine derivatives. The possible biogenesis of zoanthamines is also proposed. (C) 1997 Elsevier Science Ltd.

引用

页码：5683 / 5686

页数：4

共 7 条

[1]

ATTA-UR-RAHMAN, 1989, Tetrahedron Letters, V30, P6825

[2]

Fukuzawa S., 1995, HETEROCYCL COMMUN, V1, P207

[3]

KURAMOTO M, 1996, 38 S CHEM NAT PROD, P78

[4] HIGH-FIELD FT NMR APPLICATION OF MOSHER METHOD - THE ABSOLUTE-CONFIGURATIONS OF MARINE TERPENOIDS [J].

OHTANI, I ;

KUSUMI, T ;

KASHMAN, Y ;

KAKISAWA, H .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (11) :4092-4096

[5]

RAO CB, 1989, HETEROCYCLES, V28, P103

[6] ZOANTHAMINE - A NOVEL ALKALOID FROM A MARINE ZOANTHID [J].

RAO, CB ;

ANJANEYULA, ASR ;

SARMA, NS ;

VENKATATESWARLU, Y ;

ROSSER, RM ;

FAULKNER, DJ ;

CHEN, MHM ;

CLARDY, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (25) :7983-7984

[7] ALKALOIDS FROM A MARINE ZOANTHID [J].

RAO, CB ;

ANJANEYULU, ASR ;

SARMA, NS ;

VENKATESWARLU, Y ;

ROSSER, RM ;

FAULKNER, DJ .

JOURNAL OF ORGANIC CHEMISTRY, 1985, 50 (20) :3757-3760

← 1 →