Isolation of infectious Zika virus from saliva and prolonged viral RNA shedding in a traveller returning from the Dominican Republic to Italy, January 2016

被引:125
作者
Barzon, L. [1 ,2 ]
Pacenti, M. [2 ]
Berto, A. [1 ]
Sinigaglia, A. [3 ]
Franchin, E. [1 ,2 ]
Lavezzo, E. [1 ]
Brugnaro, P. [4 ]
Palu, G. [1 ,2 ]
机构
[1] Univ Padua, Dept Mol Med, Padua, Italy
[2] Padova Univ Hosp, Microbiol & Virol Unit, Padua, Italy
[3] Veneto Inst Oncol IOV IRCCS, Padua, Italy
[4] Venice City Hosp SS Giovanni & Paolo, Dept Infect Dis, Venice, Italy
关键词
WEST NILE VIRUS; RT-PCR ASSAY; TRANSMISSION; CHIKUNGUNYA; DENGUE; OUTBREAK; URINE; EPIDEMIC; REGION; STATES;
D O I
10.2807/1560-7917.ES.2016.21.10.30159
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We report the isolation of infectious Zika virus (ZIKV) in cell culture from the saliva of a patient who developed a febrile illness after returning from the Dominican Republic to Italy, in January 2016. The patient had prolonged shedding of viral RNA in saliva and urine, at higher load than in blood, for up to 29 days after symptom onset. Sequencing of ZIKV genome showed relatedness with strains from Latin America.
引用
收藏
页码:2 / 6
页数:5
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