Mono- and bis-acrolein derivatives by reliable and efficient one-step methylenation of aldehyde precursors

被引：10

作者：

Basu, K ^{[1
]}

Richards, J ^{[1
]}

Paquette, LA ^{[1
]}

机构：

[1] Ohio State Univ, Evans Chem Labs, Columbus, OH 43210 USA

来源：

SYNTHESIS-STUTTGART | 2004年 / 17期

关键词：

alpha; beta-unsaturated aldehydes; diethylamine hydrochloride; 1,2-dichloroethane; acroleins; one-step reaction;

D O I：

10.1055/s-2004-834866

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of aldehydes carrying different functional groups was transformed directly into the a-methylene derivatives. Dialdehydes behaved comparably at both active sites. When keto aldehydes are involved, excellent levels of chemoselectivity are observed, with the ketone substructures exhibiting no sign of reactivity.

引用

页码：2841 / 2844

页数：4

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