Escherichia coli O157: What every internist and gastroenterologist should know

被引:14
作者
Bavaro M.F. [1 ]
机构
[1] Infectious Diseases Division, Naval Medical Center San Diego, San Diego, CA 92134
关键词
Hemolytic Uremic Syndrome; Fosfomycin; Rifaximin; Haemolytic Uraemic Syndrome; Shiga Toxin;
D O I
10.1007/s11894-009-0044-0
中图分类号
学科分类号
摘要
Infections with Escherichia coli O157:H7 have gained media attention in recent years because of cases associated with unusual sources (eg, produce and swimming pools). Although most adults recover without sequelae, children and the elderly are more likely to develop complications (eg, hemolytic uremic syndrome and death). The diagnosis typically has been made by culture; however, newer handheld immunoassays and polymerase chain reaction technology have led to more rapid detection of this important pathogen in stools, food, and water. Treatment is largely supportive; nonetheless, new methods to neutralize or bind toxin, such as probiotics, monoclonal antibodies, and recombinant bacteria, are showing promise to treat patients infected with E. coli O157:H7. The role of antibiotics in relation to this condition remains unclear. © Current Medicine Group, LLC 2009.
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页码:301 / 306
页数:5
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