Anaplastic thyroid carcinoma: An overview

被引:73
作者
Cornett W.R. [1 ]
Sharma A.K. [1 ]
Day T.A. [1 ]
Richardson M.S. [1 ]
Hoda R.S. [1 ]
van Heerden J.A. [1 ]
Fernandes J.K. [1 ]
机构
[1] The Medical University of South Carolina, Charleston, SC 29425
关键词
Thyroid Cancer; Thyroid Carcinoma; Neck Dissection; Recurrent Laryngeal Nerve; Total Thyroidectomy;
D O I
10.1007/s11912-007-0014-3
中图分类号
学科分类号
摘要
Thyroid cancer is an uncommon malignancy that accounts for roughly 1% of all new cancer. Although anaplastic lesions constitute fewer than 5% of thyroid cancers, they represent over half of thyroid cancer-related deaths. The relative rarity of anaplastic thyroid cancer, its aggressive nature, and its rapidly fatal course have contributed to the difficulty in developing effective treatment for this disease. Radiation, chemotherapy, and surgery are rarely curative, but combinations of these modalities appear to offer greater benefit than any single treatment. New treatment modalities are desperately required, and promising molecular-based therapies are being investigated. Copyright © 2007 by Current Medicine Group LLC.
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页码:152 / 158
页数:6
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