The circumferential resection margin in rectal carcinoma surgery

被引：69

作者：

Hermanek P. ^{[1
]}

Junginger T. ^{[2
]}

机构：

[1] Department of Surgery, University of Erlangen, D-91023 Erlangen

[2] Department of General and Visceral Surgery, University of Mainz, Mainz

来源：

Techniques in Coloproctology | 2005年 / 9卷 / 3期

关键词：

Circumferential resection margin; Local recurrence; Neoadjuvant therapy; Rectal carcinoma; Survival; Total mesorectal excision;

D O I：

10.1007/s10151-005-0226-1

中图分类号：

学科分类号：

摘要：

After radical resection of rectal carcinoma, the circumferential resection margin (CRM) on the non-peritonealized surface of the resected specimen is of critical importance. Histopathological examination of resected specimens must include careful assessment of the CRM. There is a need to distinguish between CRM-positive (CRM directly involved by tumor or minimal distance between tumor and CRM 1 mm or less) and CRM-negative (distance between tumor and CRM more than 1 mm) situations. Optimized surgery (so-called TME surgery) and an experienced surgeon decrease the frequency of CRM-positive specimens. The CRM status is an important predictor of local and distant recurrence as well as survival. The CRM status can be reliably predicted by preoperative thin-slice high-resolution magnetic resonance imaging (MRI). In the event of predicted CRM-positivity, neoadjuvant radiochemotherapy is indicated.

引用

页码：193 / 200

页数：7

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