Post-surgical and obstructive gastroparesis

被引：96

作者：

Shafi M.A. ^{[1
]}

Pasricha P.J. ^{[1
]}

机构：

[1] University of Texas Medical Branch, Galveston, TX 77555-0764

来源：

Current Gastroenterology Reports | 2007年 / 9卷 / 4期

关键词：

Gastric Emptying; Gastric Electrical Stimulation; Vagal Nerve Injury;

D O I：

10.1007/s11894-007-0031-2

中图分类号：

学科分类号：

摘要：

Post-surgical gastroparesis (PSG) is recognized as a consequence of vagal nerve injury following upper abdominal surgery. It has been well documented following vagotomy for peptic ulcer surgery. With the increasing role of surgical treatment in the management of GERD and morbid obesity, PSG is now being diagnosed after fundoplication and bariatric surgery. PSG has also been reported after heart and lung transplantation, possibly due to opportunistic viral infection or motor-inhibitory effects of the immunosuppressive drugs, in addition to vagal nerve injury. Initial postoperative management of PSG should be conservative as many symptoms following abdominal surgery resolve with time. This occurs possibly because the enteric nervous system is able to adapt to the loss of vagal input or vagal reinnervation occurs. Persistent symptoms are difficult to manage and require a multidisciplinary team approach. Gastric electrical stimulation has shown promise in small series. Copyright © 2007 by Current Medicine Group LLC.

引用

页码：280 / 285

页数：5

共 36 条

[1]

Soykan I., Sivri B., Sarosiek I., Et al., Demography, clinical characteristics, psychological profiles, treatment and longterm follow-up of patients with gastroparesis, Dig Dis Sci, 43, pp. 2398-2404, (1998)

[2]

Fich A., Neri M., Camilleri M., Et al., Stasis syndromes following gastric surgery: Clinical and motility features of 60 symptomatic patients, J Clin Gastroenterol, 12, pp. 505-512, (1990)

[3]

Eagon J.C., Miedema B.W., Kelly K.A., Postgastrectomy syndromes, Surg Clin North Am, 72, pp. 445-465, (1992)

[4]

Nakamura K., Takahashi T., Taniuchi M., Et al., Nicotinic receptor mediates nitric oxide synthase expression in the rat gastric myenteric plexus, J Clin Invest, 101, pp. 1479-1489, (1998)

[5]

Schirmer B.D., Current status of proximal gastric vagotomy, Ann Surg, 209, pp. 131-148, (1989)

[6]

Koo J., Lam S.K., Chan P., Et al., Proximal gastric vagotomy, truncal vagotomy with drainage, and truncal vagotomy with antrectomy for chronic duodenal ulcer. A prospective, randomized controlled trial, Ann Surg, 197, pp. 265-271, (1983)

[7]

Mathias J.R., Fernandez A., Sninsky C.A., Et al., Nausea, vomiting, and abdominal pain after Roux-en-Y anastomosis: Motility of the jejunal limb, Gastroenterology, 88, pp. 101-107, (1985)

[8]

van der Mijle H.C., Beekhuis H., Bleichrodt R.P., Kleibeuker J.H., Transit disorders of the gastric remnant and Roux limb after Roux-en-Y gastrojejunostomy: Relation to symptomatology and vagotomy, Br J Surg, 80, pp. 60-654, (1993)

[9]

Debas H.T., Orloff S.L., Surgery for peptic ulcer disease, Textbook of Gastroenterology, 1, pp. 1379-1398, (1991)

[10]

Frantzides C.T., Carlson M.A., Zografakis J.G., Et al., Postoperative gastrointestinal complaints after laparoscopic Nissen fundoptication, JSLS, 10, pp. 39-42, (2006)

← 1 2 3 4 →