Chronic urticaria: background, evaluation, and treatment.

被引:10
作者
Charlesworth E.N. [1 ]
机构
[1] Allergy, Shannon Clinic, Department of Medicine, University of Texas Medical School at Houston, 215 E. College, San Angelo, 76903, TX
关键词
Mast Cell; Urticaria; Angioedema; Allergy Clin Immunol; Terfenadine;
D O I
10.1007/s11882-001-0046-y
中图分类号
学科分类号
摘要
Urticaria and angioedema will affect 15% of the general population during their lifetime, and this remains one of the most vexing cutaneous conditions to evaluate and treat. Patients frequently go from one physician to another in hopes of finding a healthcare provider who can identify the cause and cure the ailment. Physicians treating hives are equally frustrated as they ponder the utility of obtaining a panel of screening laboratory tests that have previously been shown to have a low yield or obtaining selected allergy tests in a group of patients who are no more prone to allergic disease than the general public. This review presents recent information in a clinical context with the aim of aiding the physician in understanding the pathophysiology of urticaria and formulating an intelligent evaluation and treatment plan.
引用
收藏
页码:342 / 347
页数:5
相关论文
共 60 条
[1]  
Charlesworth EN(1989)Cutaneous late-phase response to allergen: mediator release and inflammatory cell infiltration J Clin Invest 83 1519-1526
[2]  
Hood AF(1986)A serological mediator in chronic idiopathic urticaria: a clinical immunological and histological evaluation Br J Dermatol 114 583-590
[3]  
Soter NA(1993)Autoantibodies against the high affinity IgE receptor as a cause for histamine release in chronic urticaria N Engl J Med 328 1599-1604
[4]  
Grattan CE(1996)Dermal mast cell activation by autoantibodies against the high affinity IgE receptor in chronic urticaria J Invest Dermatol 106 1001-1006
[5]  
Wallington TB(1995)Serum IgG autoantibodies directed against the alpha chain of the FceRI: a selective marker and pathogenetic factor for a distinct subset of chronic urticaria: a pathogenetic factor for a distinct subset of chronic urticaria patients J Clin Invest 96 2606-2612
[6]  
Warin RP(1999)Cutaneous inflammatory cell infiltrate in chronic idiopathic urticaria: comparison of patients with and without anti-FceRIa or anti-IgE autoantibodies J Allergy Clin Immunol 103 484-493
[7]  
Hide M(1996)Urticaria and angioedema: a clinical spectrum Ann Allergy Asthma Immunol 76 484-496
[8]  
Francis DM(1998)Role of food allergy and food intolerance in recurrent urticaria Curr Probl Dermatol 28 64-73
[9]  
Grattan CE(1996)Food hypersensitivity among adult patients: epidemiological and clinical aspects Allergol Immunopathol (Madr) 24 93-97
[10]  
Greaves MW(2000)Chronic urticaria J Allergy Clin Immunol 105 644-672