Pain sensitivity in chronic psychoemotional stress in humans

被引:31
作者
Ashkinazi I.Y. [2 ]
Vershinina E.A. [1 ]
机构
[1] Neurosis Laboratory, Russian Academy of Sciences, 6 Makarov Bank, St. Petersburg
[2] Applied Mathematics Group, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, 6 Makarov Bank, St. Petersburg
关键词
Chronic psychoemotional stress; Focused ultrasound; Pain sensitivity;
D O I
10.1007/BF02465346
中图分类号
学科分类号
摘要
Results were obtained from comparative studies of skin pain sensitivity (pain thresholds) using focused ultrasound in 51 healthy men and 101 patients with neurasthenia. Neurasthenia is a natural "model" of chronic psychoemotional stress, and patients showed a reduction in the pain threshold which was not accompanied by a reduction in the threshold of sensitivity to tactile stimulation. A reduction in the pain threshold, reflecting a weakening of central descending tonic inhibition, was probably due to a reduction in the activity of the brain's opioid system during long-term psychoemotional stress. Analysis of the relationships between the pain sensitivity threshold and pain syndromes suggests a role for changes in the nociception system in chronic psychoemotional stress, as part of the mechanism of pain formation. © 1999 Kluwer Academic/Plenum Publishers.
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页码:333 / 337
页数:4
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