Agonistic behavior during stress prevents the development of learned helplessness in rats

被引：7

作者：

Zhukov D.A. ^{[1
]}

Vinogradova E.P. ^{[2
]}

机构：

[1] I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, 6 Makarov Bank

[2] Department of Higher Nervous Activity, St. Petersburg State University, 7/9 Universitetskaya Bank

来源：

Neuroscience and Behavioral Physiology | 1998年 / 28卷 / 2期

关键词：

Aggression; Learned helplessness; Unavoidable stress;

D O I：

10.1007/BF02461969

中图分类号：

学科分类号：

摘要：

Male Wistar rats were subjected to unavoidable electrical pain stimulation either in individual cages or in pairs. During the procedure, rats stressed in pairs fought. After 48 h, rats were tested in a shuttle box for the ability to develop active avoidance responses. The proportion of escape and avoidance responses was significantly lower in rats stressed individually as compared with intact animals and animals stressed in pairs. Plasma corticosterone was assayed one day later, at rest and after dexamethasone administration. There were no significant differences in resting corticosterone levels between groups of animals. Administration of dexamethasone significantly reduced the plasma corticosterone level in intact rats and in animals stressed in pairs. But not in rats stressed individually. Thus, agonistic behavior during unavoidable stress prevents the development of pathological changes in adaptive behavior and the endocrine system. ©1998 Plenum Publishing Corporation.

引用

页码：206 / 210

页数：4

共 25 条

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