Using bone densitometry to monitor therapy in treating osteoporosis: pros and cons.

被引：10

作者：

Deal C.L. ^{[1
]}

机构：

[1] Center for Osteoporosis and Metabolic Disease, The Cleveland Clinic Foundation

[2] Immunologic Diseases, Desk A-50, 9500 Euclid Avenue, Cleveland, 44195, OH

来源：

Current Rheumatology Reports | 2001年 / 3卷 / 3期

关键词：

Vertebral Fracture; Alendronate; Raloxifene; Risedronate; Bone Densitometry;

D O I：

10.1007/s11926-001-0023-4

中图分类号：

学科分类号：

摘要：

Measurement of bone density is crucial for evaluating fracture risk. Low bone mass is a powerful predictor of fracture and is necessary to assess the need for treatment. Dual energy x-ray absorptiometry is accurate and precise. Use of bone density for monitoring therapy is an important tool for evaluating response to therapy, but an understanding of the limitations of the procedure are important for the practicing physician. Precision error of the technology and what change in density is clinically significant (least significant change) are important concepts to interpret results and make appropriate treatment decisions. This article reviews the use of bone densitometry as a tool for monitoring treatment in patients with low bone mass.

引用

页码：233 / 239

页数：6

共 72 条

[1]

Curry JD(1986)Power law models for the mechanical properties of cancellous bone Eng Med 15 153-154

[2]

Turner CH(1989)Yield behavior of cancellous bone J Biomech Eng 111 1-5

[3]

Hui SL(1989)Baseline measurement of bone mass predicts fracture in white women Ann Int Med 111 355-361

[4]

Slemenda CW(1993)Bone density at various sites for prediction of hip fractures Lancet 341 72-75

[5]

Johnston CC(1993)Long-term fracture prediction by bone mineral assessed at different skeletal sites J Bone Mineral Res 8 1227-1233

[6]

Cummings SR(1999)Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial JAMA 282 637-645

[7]

Black DM(1996)Randomized trial of effect of alendronate on risk of fracture in women with existing vertebral fractures Lancet 348 1535-1541

[8]

Nevitt MC(1986)Should perimenopausal women be screened for osteoporosis Ann Intern Med 104 817-823

[9]

Melton JL(1999)Monitoring skeletal changes by radiological techniques J Bone Min Res 14 1952-1962

[10]

Atkinson EJ(1998)Effect of alendronate on risk of fracture in women with low bone density but without vertebral fracture JAMA 280 2077-2082

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