Recent advances in the management of acute intracerebral hemorrhage

被引：6

作者：

Bernstein R.A. ^{[1
]}

Del-Signore M. ^{[1
]}

机构：

[1] Ken and Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611

来源：

Current Neurology and Neuroscience Reports | 2005年 / 5卷 / 6期

关键词：

Intracerebral Hemorrhage; Intraventricular Hemorrhage; Clot Lysis; Hematoma Volume; Hematoma Expansion;

D O I：

10.1007/s11910-005-0038-8

中图分类号：

学科分类号：

摘要：

Intracerebrall hemorrhage (ICH) is the most deadly form of stroke, and its acute treatment has suffered from a lack of guidance by reliable clinical trial data. In the past year, however, important clinical trials have helped point toward effective acute management. Studies have shown that magnetic resonance imaging is as accurate as computed tomography in diagnosing acute ICH, although this study is not always feasible in critically ill patients. Ultra-early hemostatic therapy has shown promise in limiting early hematoma expansion and rebleeding. The role of early surgery in patient management has been partially clarified. Finally, a novel treatment for intraventricular hemorrhage has shown promise in speeding clot resolution. All of these advances provide grounds for optimism that multimodal, evidence-based treatment of acute ICH will be reality in the near future. Copyright © 2005 by Current Science Inc.

引用

页码：483 / 487

页数：4

共 28 条

[1]

Kidwell C.S., Chalela J.A., Saver J.L., Et al., Comparison of MRI and CT for detection of acute intracerebral hemorrhage, JAMA, 292, pp. 1823-1830, (2004)

[2]

Fiebach J.B., Schellinger P.D., Gass A., Et al., Stroke magnetic resonance imaging is accurate in hyperacute intracerebral hemorrhage: A multicenter study on the validity of stroke imaging, Stroke, 35, pp. 502-506, (2004)

[3]

Singer O.C., Sitzer M., du Mesnil de Rochemont R., Neumann-Haefelin T., Practical limitations of acute stroke MRI due to patient-related problems, Neurology, 62, pp. 1848-1849, (2004)

[4]

Matsumoto K., Sakaki S., Abekura M., Yoshimine T., Co-existence of unruptured cerebral aneurysms in patients with hypertensive intracerebral hemorrhage, Acta Neurochir., 146, pp. 1085-1089, (2004)

[5]

Brott T., Broderick J., Kothari R., Et al., Early hemorrhage growth in patients with intracerebral hemorrhage, Stroke, 28, pp. 1-5, (1997)

[6]

Hemphill III J.C., Bonovich D.C., Besmertis L., Et al., The ICH score: A simple, reliable grading scale for intracerebral hemorrhage, Stroke, 32, pp. 891-897, (2001)

[7]

Kazui S., Naritomi H., Yamamoto H., Et al., Enlargement of spontaneous intracerebral hemorrhage. Incidence and time course, Stroke, 27, pp. 1783-1787, (1996)

[8]

Ohwaki K., Yano E., Nagashima H., Et al., Blood pressure management in acute intracerebral hemorrhage: Relationship between elevated blood pressure and hematoma enlargement, Stroke, 35, pp. 1364-1367, (2004)

[9]

Mayer S.A., Ultra-early hemostatic therapy for intracerebral hemorrhage, Stroke, 34, pp. 224-229, (2003)

[10]

Mayer S.A., Brun N.C., Begtrup K., Et al., Recombinant activated factor VII for acute intracerebral hemorrhage, N. Engl. J. Med., 352, pp. 777-785, (2005)

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