Colorectal carcinoma: Is screening possible?

被引：4

作者：

Bonelli L. ^{[1
]}

机构：

[1] U. of Secdry. Prev. and Screening, Natl. Institute for Cancer Research, I-16132 Genoa

来源：

Techniques in Coloproctology | 2004年 / 8卷 / Suppl 2期

关键词：

Colonoscopy; Colorectal cancer screening; Evidence of benefits; Faecal occult blood tests; Sigmoidoscopy;

D O I：

10.1007/s10151-004-0174-1

中图分类号：

学科分类号：

摘要：

Colorectal cancer (CRC) is a major health problem in western countries. It is the most frequently diagnosed cancer in EU countries with about 220 000 new cases per year; the number of CRC deaths approaches 112 000. Most cancer arises from adenomatous polyps through the adenoma-carcinoma sequence; the natural history of the disease is long: the risk of invasive cancer in adenoma is about 2% per year. Given the natural history of CRC, early diagnosis represents the most appropriate tool to reduce the disease-related mortality. Several tests are available to screen healthy subjects at average risk for CRC: faecal occult blood tests, flexible sigmoidoscopy, combined faecal occult blood tests and flexible sigmoidoscopy, total colonoscopy and double contrast barium enema. Issues related to the introduction on a large scale of population-based screening programmes for CRC are discussed.

引用

页码：S267 / S272

页数：5

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