Lumbar punctures: Use and diagnostic efficiency in emergency medical departments

被引:13
作者
Majed B. [1 ,2 ]
Zephir H. [3 ]
Pichonnier-Cassagne V. [1 ]
Yazdanpanah Y. [4 ]
Lestavel P. [5 ]
Valette P. [1 ]
Vermersch P. [3 ]
机构
[1] Emergency Medicine Department, Unit of Epidemiology and Clinical Research, Arras General Hospital, Arras 62000, Boulevard Besnier
[2] Biostatistics Department, Curie Institute, Paris 75005
[3] Neurology Department, Roger Salengro Hospital, CHRU de Lille
[4] Service des Maladies Infectieuses et du Voyageur, Centre Hospitalier de Tourcoing, 59208 Tourcoing
[5] Emergency Department, Hénin-Beaumont Polyclinic, 62256 Hénin-Beaumont, Route de Courrière
关键词
Diagnosis; Efficiency; Emergency medical department; Lumbar puncture; Medical practice assessment; Meningitis;
D O I
10.1007/s12245-009-0128-5
中图分类号
学科分类号
摘要
Background: Lumbar punctures (LP) are regularly and effortlessly used in the emergency medical departments (EMD). LP use and efficiency have not been fully explored in the published literature. Aims: The goal of this study was to assess in a French EMD, the frequency of use and the diagnostic efficiency of LP, the final diagnoses, and related medical practices. Methods: We retrospectively studied all patients who underwent an LP after admission to our adult EMD in 2004 and 2005. Patients' medical files were reviewed to collect clinical and paraclinical features. We defined efficient LP as abnormal LP, which confirmed a suspected diagnosis in an emergency setting. Results: A total of 247 patients, representing 0.5% of all admissions, underwent an LP. LP were efficient in fewer than 15% of cases and confirmed aseptic meningitis (8.5%), bacterial meningitis (2.4%), Guillain-Barré syndromes (1.6%), subarachnoid hemorrhages (SAH, 0.4%), and carcinomatous meningitis (0.4%). The principal differential diagnoses were infections outside the central nervous system (CNS, 30%), noninfectious neurological disorders (28.7%), and benign headaches (14.2%). The main assumed LP indications were to search for CNS infection (62%) and for SAH (25%). LP efficiency decreased dramatically according to patients' age. Brain imaging was performed in 90% of patients prior to LP. Excessive use of polymerase chain reaction to detect herpes simplex in cerebrospinal fluid was observed. The only LP complications found were postdural puncture headaches (6.1% of cases). The rate of traumatic LP was 17%. Conclusions: Our results are in accordance with the few published surveys on this topic. LP efficiency is modest but must be considered in light of the seriousness of suspected diagnoses. However, the search for differential diagnoses should not be neglected. © 2009 Springer-Verlag London Ltd.
引用
收藏
页码:227 / 235
页数:8
相关论文
共 48 条
[1]
Powers R.D., Emergency department lumbar puncture: Clinical application and utility of laboratory testing, Am J Emerg Med, 5, 6, pp. 516-520, (1987)
[2]
Sharief M., Lumbar puncture and CSF examination, Medicine, 32, 9, pp. 44-46, (2004)
[3]
Fitch M.T., Van De Beek D., Emergency diagnosis and treatment of adult meningitis, Lancet Infectious Diseases, 7, 3, pp. 191-200, (2007)
[4]
O'Neill J., McLaggan S., Gibson R., Acute headache and subarachnoid haemorrhage: A retrospective review of CT and lumbar puncture findings, Scott Med J, 50, 4, pp. 151-153, (2005)
[5]
McGillicuddy D.C., Walker O., Shapiro N.I., Edlow J.A., Guillain-Barré syndrome in the emergency department, Ann Emerg Med, 47, 4, pp. 390-393, (2006)
[6]
Al-Shahi R., White P.M., Davenport R.J., Lindsay K.W., Subarachnoid haemorrhage, BMJ, 333, 7561, pp. 235-240, (2006)
[7]
Fletcher D.D., Lawn N.D., Wolter T.D., Wijdicks E.F., Long-term outcome in patients with Guillain-Barré syndrome requiring mechanical ventilation, Neurology, 54, 12, pp. 2311-2315, (2000)
[8]
Modol J.M., Tudela P., Veny A., Sahuquillo J.C., Tor J., Gimenez M., Indications and diagnosis efficiency of lumbar puncture in emergencies (in Spanish), Med Clin (Barc), 118, 1, pp. 10-12, (2002)
[9]
Perry J.J., Stiell I., Wells G., Spacek A., Diagnostic test utilization in the emergency department for alert headache patients with possible subarachnoid hemorrhage, CJEM, 4, 5, pp. 333-337, (2002)
[10]
Warshaw G., Tanzer F., The effectiveness of lumbar puncture in the evaluation of delirium and fever in the hospitalized elderly, Arch Fam Med, 2, 3, pp. 293-297, (1993)