Neonatal sepsis: Staphylococcus aureus as the predominant pathogen

被引：51

作者：

Karthikeyan G. ^{[1
]}

Premkumar K. ^{[1
]}

机构：

[1] Department of Paediatrics, Government Kasturiba Gandhi Hospital for Women and Children

来源：

The Indian Journal of Pediatrics | 2001年 / 68卷 / 8期

关键词：

Antimicrobial resistance; Neonatal sepsis; Staphylococcus aureus;

D O I：

10.1007/BF02752407

中图分类号：

学科分类号：

摘要：

96 consecutive inborn neonates with blood culture proven bacterial sepsis during the period January to June 1997 were studied. Lethargy with refusal of feeds (28%), fever (28%) and respiratory distress (31.3%) were the major presenting features. Half of them (n=48) were of early onset (< 48 hours) and the remaining half were of late onset (> 48 hours). Staphylococcus aureus (n=59, 61.5%) was the predominant pathogen and 66% of them were methicillin resistant followed by Klebsiella pnemoniae (n=24, 21.9), Escherichia coli (n=13, 13.5%) and streptococci (n=3, 3.1%). Antibiotic resistance was common, with the sensitivity to various antibiotics being ampicillin 1.9%, gentamicin 21.6%, cefotaxime 32.8%, amikacin 50%, chloromycetin 59.6% and ciprofloxacin 90.3%.

引用

页码：715 / 717

页数：2

共 14 条

[1]

Neonatal morbidity and mortality: Report of the Natlonal Neonatal-Perinatal Database, Ind Pediatr, 34, pp. 1039-1042, (1997)

[2]

Gerdes J.S., Clinicopathological approach to the diagnosis of neonatal sepsis, Isr J Med Scien, 30, pp. 430-441, (1994)

[3]

Mondal G.P., Mayaraghavan B., Bhat B.V., Et al., Neonatal septicemia among inborn and outborn babies in a referral hospital, Ind J Pediatr, 58, pp. 529-533, (1991)

[4]

Kathua S.P., Das A.K., Chatterjee B.D., Neonatal septicemia, Ind J Pediatr, 53, pp. 509-514, (1986)

[5]

Bhakoo O.N., Narang A., Kulkarni K.N., Neonatal morbidity and mortality in hospital born babies, Ind Pediatr, 12, pp. 443-450, (1975)

[6]

Kaushik, Grover N., Parmer V.R., Grover P.S., Kaushi K.R., Neonatal morbidity in a hospital at Shimla, Ind J Pediatr, 66, pp. 15-19, (1999)

[7]

Isaacs D., Barfield C.P., Grimwood K., Et al., Systemic bacterial and fungal infections in infants in Australian neonatal units, Med J Austr, 162, pp. 198-201, (1995)

[8]

Thomas M., Padmini B., Srimathi G., Sundararajan V., Raju B.A., Microbiological profile of neonatal infections in Coimbatore, Ind J Pediatr, 66, pp. 11-14, (1999)

[9]

Pildes R.S., Ramamurthy R.S., Vidyasagar D., Effect of triple dye on staphylococcal colonization in the newborn infant, J Pediatr, 82, pp. 887-890, (1973)

[10]

Coyer W.F., Neonatal skin care and the prevention of S. aureus colonization, Pediatr Res, 9, pp. 339-340, (1975)

← 1 2 →