Herbal plants and plant preparations as remedial approach for viral diseases

被引：78

作者：

Ganjhu R.K. ^{[1
]}

Mudgal P.P. ^{[1
]}

Maity H. ^{[1
]}

Dowarha D. ^{[1
]}

Devadiga S. ^{[1
]}

Nag S. ^{[2
]}

Arunkumar G. ^{[1
]}

机构：

[1] Department of Virus Research (Manipal Centre for Virus Research), Manipal University, Manipal, 576104, Karnataka

[2] Department of Zoology, Ranchi University, Ranchi, 834001, Jharkhand

来源：

VirusDisease | 2015年 / 26卷 / 4期

关键词：

Antiviral; Ethnopharmacology; Herbal preparations; Patent information; Viral diseases;

D O I：

10.1007/s13337-015-0276-6

中图分类号：

学科分类号：

摘要：

Herbal plants, plant preparations and phytoconstituents have proved useful in attenuating infectious conditions and were the only remedies available, till the advent of antibiotics (many being of plant origin themselves). Among infectious diseases, viral diseases in particular, remain the leading cause of death in humans globally. A variety of phytoconstituents derived from medicinal herbs have been extensively studied for antiviral activity. Based on this rationale, an online search was performed, which helped to identify a large number of plant species harboring antiviral molecules. These herbal sources have been reported individually or in combinations across a large number of citations studied. Activities against rabies virus, Human immunodeficiency virus, Chandipura virus, Japanese Encephalitis Virus, Enterovirus, Influenza A/H1N1 and other influenza viruses were discovered during the literature search. This review includes all such plant species exhibiting antiviral properties. The review also encompasses composition and methodologies of preparing various antiviral formulations around the globe. An elaborate section on the formulations filed for patent registration, along with non-patented formulations, has also been included in this article. To conclude, herbal sources provide researchers enormous scope to explore and bring out viable alternatives against viral diseases, considering non-availability of suitable drug candidates and increasing resistance to existing drug molecules for many emerging and re-emerging viral diseases. © 2015, Indian Virological Society.

引用

页码：225 / 236

页数：11

共 111 条

[1]

Abdallah R.M., Ghazy N.M., El-Sebakhy N.A., Pirillo A., Verotta L., Astragalosides from Egyptian Astragalus spinosus Vahl, Pharmazie, 48, 6, pp. 452-454, (1993)

[2]

Alvarez A.L., Habtemariam S., Juan-Badaturuge M., Jackson C., Parra F., In vitro anti HSV-1 and HSV-2 activity of Tanacetum vulgare extracts and isolated compounds: an approach to their mechanisms of action, Phytother Res, 25, 2, pp. 296-301, (2011)

[3]

Babar M., Najam-us-Sahar S.Z., Ashraf M., Kazi A.G., Antiviral drug therapy- exploiting medicinal plants, J Antivir Antiretrovir, 5, pp. 28-36, (2013)

[4]

Bennerman R., Burton J., Chen W.C., plants .M., an agenda for action. Traditional medicine and health care coverage

[5]

Geneva, (1983)

[6]

Bertol J.W., Rigotto C., de Padua R.M., Kreis W., Barardi C.R., Braga F.C., Et al., Antiherpes activity of glucoevatromonoside, a cardenolide isolated from a Brazilian cultivar of Digitalis lanata, Antiviral Res, 92, 1, pp. 73-80, (2011)

[7]

Bliah M.A.M., Anti viral composition, Google Patents, (1987)

[8]

Chavali S.R., Barton L.D., Campbell J.B., Immunopotentiation by orally-administered Quillaja saponins: effects in mice vaccinated intraperitoneally against rabies, Clin Exp Immunol, 74, 3, pp. 339-343, (1988)

[9]

Chen G.F., Huang W.G., Chen F.Y., Shan J.L., Protective effects of trichosanthin in Herpes simplex virus-1 encephalitis in mice, Zhongguo Dang Dai Er Ke Za Zhi, 8, 3, pp. 239-241, (2006)

[10]

Chen Z.-H., Hong-yuan L.I., XIE Z.-P., Antiviral active compound (RG3-1) from radix gentianae and its anti-RSV activity in vitro, J Harbin Med Univ, 4, (2007)

← 1 2 3 4 5 6 7 8 9 10 →