Acute lung injury/acute respiratory distress syndrome (ALI/ARDS): the mechanism, present strategies and future perspectives of therapies

被引:113
作者
Luh S.-P. [1 ]
Chiang C.-H. [2 ]
机构
[1] Department of Surgery, Chung-Shan Medical University Hospital, Taichung
[2] Division of Pulmonary Immunology and Infectious Diseases, Taipei Veterans General Hospital, Taipei
关键词
Acute lung injury; Acute respiratory distress syndrome; Cell therapy; R56; Ventilator;
D O I
10.1631/jzus.2007.B0060
中图分类号
学科分类号
摘要
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS), which manifests as non-cardiogenic pulmonary edema, respiratory distress and hypoxemia, could be resulted from various processes that directly or indirectly injure the lung. Extensive investigations in experimental models and humans with ALI/ARDS have revealed many molecular mechanisms that offer therapeutic opportunities for cell or gene therapy. Herein the present strategies and future perspectives of the treatment for ALI/ARDS, include the ventilatory, pharmacological, as well as cell therapies. © 2007, Springer-Verlag.
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页码:60 / 69
页数:9
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