Genetic influences on attention deficit hyperactivity disorder

被引:70
作者
Faraone S.V. [1 ]
Doyle A.E. [2 ]
机构
[1] Harvard Institute of Psychiatry, Epidemiology, and Genetics, Department of Psychiatry, Massachusetts Hospital Center, Harvard University, South Easton, MA, 02375, 750 Washington Street
[2] Clinical and Research Program in Pediatric Psychopharmacology, Child Psychiatry, ACC-725, Massachusetts General Hospital, Boston, MA, 02114
关键词
Attention Deficit Hyperactivity Disorder; Attention Deficit Hyperactivity Disorder; Molecular Genetic Study; Acad Child Adolesc Psychiatry; Attention Deficit Disorder;
D O I
10.1007/s11920-000-0059-6
中图分类号
学科分类号
摘要
In this article we review behavioral and molecular genetics studies of attention deficit hyperactivity disorder (ADHD). Family, twin, and adoption studies, along with segregation analyses and molecular genetic studies, all support the hypothesis that both genetic and environmental factors contribute to the etiology of ADHD. Despite this strong evidence for the familial transmission of ADHD, the mode of transmission requires further clarification. In addition, because ADHD appears to be genetically heterogeneous, more work is needed to delineate genetically homogeneous subtypes and describe the range of expression of their underlying genotypes.
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页码:143 / 146
页数:3
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