Electrospun nanofibers of collagen-chitosan and P(LLA-CL) for tissue engineering

被引：18

作者：

Mo X. ^{[1
]}

Chen Z. ^{[1
]}

Weber H.J. ^{[2
]}

机构：

[1] Institute of Biological Science and Biotechnology, Donghua University

[2] Department of Biomedical Engineering, Aachen University of Applied Sciences, 201620 Juelich

来源：

Frontiers of Materials Science in China | 2007年 / 1卷 / 1期

关键词：

Chitosan; Collagen; Electrospinning; Nanofiber; P(LLA-CL); Tissue engineering;

D O I：

10.1007/s11706-007-0004-2

中图分类号：

学科分类号：

摘要：

Electrospun nanofibers could be used to mimic the nanofibrous structure of the extracellular matrix (ECM) in native tissue. In tissue engineering, the ECM could be used as tissue engineering scaffold to solve tissue engineering problems. In this paper, poly(L-lactid-co-caprolactone) [P(LLA-CL)] nanofibers and collagen-chitosan complex nanofibers were fabricated by electrospinning. Results of the experiments showed that the mechanical properties of the collagen-chitosan complex nanofibers varied with the collagen content in the complex. It was also found that the biodegradability of P(LLA-CL) nanofibers was faster than its membrane and that smooth muscle cells (SMC) grow faster on collagen nanofibers than on P(LLA-CL) nanofibers. © Higher Education Press 2007.

引用

页码：20 / 23

页数：3

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