Hypertriglyceridemic waist may explain ethnic differences in hypertension among patients with type 2 diabetes in Sweden

被引：2

作者：

Marina Taloyan

Nuha Saleh-Stattin

Sven-Erik Johansson

Lars Agréus

Per Wändell

机构：

[1] Karolinska Institutet, Centre for Family and Community Medicine, Huddinge, SE, 141 83

[2] Stress Research Institute, Stockholm University, Stockholm

[3] Centre for Primary Health Care Research, Region Skåne, Lund University, Malmö

来源：

BMC Research Notes | / 5卷 / 1期

关键词：

Ethnicity; Hypertension; Hypertriglyceridemic waist; Sweden; Type; 2; diabetes;

D O I：

10.1186/1756-0500-5-474

中图分类号：

学科分类号：

摘要：

Background: Hypertension is common among persons with type 2 diabetes. The aim of this study was to analyze the association between ethnicity and hypertension prevalence after adjusting for age, sex, Hba1c, total cholesterol, elevated triglycerides and hypertriglyceridemic waist. The study population consisted of 354 primary health care patients diagnosed with type 2 diabetes (173 Assyrians/Syrians and 181 Swedes) residing in Södertälje, Sweden. Unconditional logistic regression was used to analyze the data. Results: Hypertension prevalence was higher among Swedes than Assyrians/Syrians, (77% versus 58%; p=0.001). In the unadjusted logistic regression model, the odds ratio for hypertension in Swedes was twice as high than that in Assyrians/Syrians (OR=2.44; 95% CI =1.54-3.86). In the age- and sex-adjusted model, odds ratio of hypertension was 2.25 (95% CI 1.41-3.60). After adjustments for total cholesterol was made, the odds ratio of hypertension decreased slightly to 1.73. When elevated triglycerides and hypertriglyceridemic waist were separately introduced, the odds ratio of hypertension was no longer significant between the ethnic groups (1.60 and 1.43 for triglycerides and hypertriglyceridemic waist respectively). In addition, advanced age - 60-69 years old (OR=1.80, CI 95% 1.00-3.20) and70 years old (OR=2.88, CI 95% 1.40-5.93), elevated total cholesterol (OR=1.48, CI 95% 1.12-1.95) and presents of hypertriglyceridemic waist (those with high WC and high TG) were significant confounding factors for the increased risk of hypertension independent of ethnicity. Conclusions: The crude differences in prevalence of hypertension between the Swedes and Assyrians/Syrians in our study population with type 2 diabetes were no longer significant when adjusting for high triglycerides levels or the presence of hypertriglyceridemic waist. © 2012 Taloyan et al.; licensee BioMed Central Ltd.

引用

共 38 条

[1]

Selvin E., Meta-analysis: Glycosylated hemoglobin and cardiovascular disease in diabetes mellitus, Ann Intern Med, 141, 6, pp. 421-431, (2004)

[2]

Deshpande A.D., Harris-Hayes M., Schootman M., Epidemiology of diabetes and diabetes-related complications, Phys Ther, 88, 11, pp. 1254-1264, (2008)

[3]

Stratton I.M., Cull C.A., Adler A.I., Matthews D.R., Neil H.A.W., Holman R.R., Additive effects of glycaemia and blood pressure exposure on risk of complications in type 2 diabetes: A prospective observational study (UKPDS 75), Diabetologia, 49, 8, pp. 1761-1769, (2006)

[4]

Kannel W.B., Castelli W.P., Gordon T., Cholesterol in the prediction of atherosclerotic disease, New Perspectives Based on the Framingham Study. Ann Intern Med, 90, 1, pp. 85-91, (1979)

[5]

Carlsson A.C., Wandell P.E., De Faire U., Hellenius M.-L., Risk factors associated with newly diagnosed high blood pressure in men and women, American Journal of Hypertension, 21, 7, pp. 771-777, (2008)

[6]

Yao X.G., The prevalence of hypertension, obesity and dyslipidemia in individuals of over 30 years of age belonging to minorities from the pasture area of Xinjiang, BMC Publ Health, 10, (2010)

[7]

Thuy A.B., The association between smoking and hypertension in a population-based sample of Vietnamese men, J Hypertens, 28, 2, pp. 245-250, (2010)

[8]

Hackam D.G., The 2010 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 2 - Therapy, Can J Cardiol, 26, 5, pp. 249-258, (2010)

[9]

Banda J.A., Protective health factors and incident hypertension in men, Am J Hypertens, 23, 6, pp. 599-605, (2010)

[10]

Ehret G.B., Genome-wide association studies: Contribution of genomics to understanding blood pressure and essential hypertension, Curr Hypertens Rep, 12, 1, pp. 17-25, (2010)

← 1 2 3 4 →