In Vitro Permeability Across Caco-2 Cells (Colonic) Can Predict In Vivo (Small Intestinal) Absorption in Man—Fact or Myth

被引：80

作者：

Shiyin Yee

机构：

[1] Pfizer Inc.,

[2] Central Research,undefined

来源：

Pharmaceutical Research | 1997年 / 14卷

关键词：

Caco-2; absorption; prediction; human; P-glycoprotein; transport;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Purpose. To evaluate and optimize the use of Caco-2 cell monolayers to predict thein vivo absorption of a broad range of compounds in man.

引用

页码：763 / 766

页数：3

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