Vitamin D deficiency in patients with chronic liver disease and cirrhosis

被引:52
作者
Lim L.Y. [1 ]
Chalasani N. [1 ]
机构
[1] Division of Gastroenterology and Hepatology, Indiana University, School of Medicine, Indianapolis, IN 46202
关键词
Cirrhosis; Fatty liver; Hepatitis C; Vitamin D;
D O I
10.1007/s11894-011-0231-7
中图分类号
学科分类号
摘要
Vitamin D is now widely recognized to have multiple extraskeletal health functions. The liver is one of the major organs involved in its metabolism. Recent studies have demonstrated a very high prevalence of vitamin D deficiency and insufficiency in patients with chronic liver disease and cirrhosis. There is an emerging interest to explore the relationship between vitamin D deficiency and prevalence and severity of non-alcoholic liver disease and response to antiviral therapy in hepatitis C. In this review, we discuss the current status of our understanding of vitamin D metabolism and vitamin D deficiency in patients with chronic liver disease and cirrhosis. © 2011 Springer Science+Business Media, LLC.
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页码:67 / 73
页数:6
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