Clinical study on acupuncture in treating diarrhea-predominant irritable bowel syndrome

被引:23
作者
Liu H.-R. [1 ]
Yang Y. [1 ]
Wu H.-G. [1 ]
机构
[1] Shanghai Research Institute of Acupuncture and Meridian
关键词
5-HT; Acupuncture-moxibustion therapy; Indirect moxibustion; Irritable bowel syndrome; Serotonin;
D O I
10.1007/s11726-008-0360-1
中图分类号
学科分类号
摘要
Objective: To observe the changes of 5-hydroxytryptamine (5-HT) in colonic membrane of diarrhea-predominant irritable bowel syndrome (IBS-D) and the clinical efficacy of herbal cake-partitioned moxibustion in treating it, and to explore the action mechanisms. Methods: Seventy-three subjects were randomized into two groups: moxibustion group in which 37 cases were treated by herbal cake-partitioned moxibustion and needling group in which 36 cases were treated by needling. The clinical efficacy and 5-HT expression in colonic membrane were observed. Results: The cure rate was 43.2% in the moxibustion group and 36.1% in the needling group, with no significant difference between the two groups (P > 0.05). Herbal cake-partitioned moxibustion could reduce 5-HT expression in colonic membrane. Conclusion: Herbal cake-partitioned moxibustion might improve the clinical symptoms of IBS-D by reducing 5-HT expression. © Shanghai Research Institute of Acupuncture and Meridian and Springer-Verlag GmbH 2008.
引用
收藏
页码:360 / 362
页数:2
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