Leksell gamma knife radiosurgery for cerebral arteriovenous malformations in pediatric patients

被引：35

作者：

Nicolato A. ^{[1
]}

Foroni R. ^{[1
]}

Seghedoni A. ^{[1
]}

Martines V. ^{[1
]}

Lupidi F. ^{[1
]}

Zampieri P. ^{[1
]}

Sandri M.F. ^{[2
]}

Ricci U. ^{[1
]}

Mazza C. ^{[1
]}

Beltramello A. ^{[1
]}

Gerosa M. ^{[1
]}

Bricolo A. ^{[1
]}

机构：

[1] Department of Neurosurgery, University Hospital, 37126 Verona

[2] Interdept. Ctr. of Economic Docum., University of Verona, 37126 Verona

来源：

Child's Nervous System | 2005年 / 21卷 / 4期

关键词：

Arteriovenous malformations; Brain; Children; Gamma knife; Prognosis; Radiosurgery;

D O I：

10.1007/s00381-004-1049-5

中图分类号：

学科分类号：

摘要：

Objects: The authors report their experience of gamma knife radiosurgery (GKR) in a large series of pediatric cerebral arteriovenous malformations (cAVMs). The advantages, risks and failures of this approach are presented and discussed. Methods: Gamma knife radiosurgery was performed on 63 children aged ≥16 years. Haemorrhage was the clinical onset in 50 out of 63 cases. The mean pre-GK cAVM volume was 3.8 cm3. Fifty-eight out of 63 cAVMs were Spetzler-Martin grades I - III. Most lesions (47 out of 63) were in eloquent or deep-seated brain regions. Conclusion: Gamma kn ife radiosurgery-related complications occurred in 2 out of 47 cases with an available follow-up (1 had transient and 1 permanent morbidity). No bleeding occurred during the latency period. In 39 children with >36-month follow-up, complete cAVM occlusion was angiographically documented in 31, with a 3- and 4-year actuarial obliteration rate of 72 and 77% respectively. High rates of complete obliteration and very low frequency of permanent morbidity with no bleeding during the latency period encourage widespread application of GKR in the treatment of pediatric cAVMs. © Springer-Verlag 2005.

引用

页码：301 / 307

页数：6

共 20 条

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