Role of γδ T cells in protecting normal airway function

被引：50

作者：

Born W.K. ^{[1
]}

Lahn M. ^{[1
]}

Takeda K. ^{[2
]}

Kanehiro A. ^{[2
]}

O'Brien R.L. ^{[1
]}

Gelfand E.W. ^{[2
]}

机构：

[1] Department of Immunology, National Jewish Medical and Research Center, Denver, CO

[2] Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO

来源：

Respiratory Research | / 1卷 / 3期

基金：

美国国家卫生研究院;

关键词：

Airway hyper-responsiveness; Asthma; Lymphocytes; γδ T cells;

D O I：

10.1186/rr26

中图分类号：

学科分类号：

摘要：

Since their discovery 15 years ago, the role of γδ T cells has remained somewhat elusive. Responses of γδ T cells have been found in numerous infectious and non-infectious diseases. New evidence points to γδ T cells' functioning in the airways to maintain normal airway responsiveness or tone. In the lung, distinct subsets of γδ T cell subsets seem to have specific roles, one subset promoting allergic inflammation, the other serving a protective role. © 2000 Current Science Ltd.

引用

页码：151 / 158

页数：7