Electrophysiological properties of the bladder

被引：17

作者：

Fry C.H. ^{[1
,2
]}

Wu C. ^{[1
]}

Sui G.P. ^{[1
]}

机构：

[1] Institute of Urology and Nephrology, University College, London

[2] Institute of Urology and Nephrology, London W1P 7PN

来源：

International Urogynecology Journal | 1998年 / 9卷 / 5期

基金：

英国惠康基金;

关键词：

Action potential; Detrusor; Electrophysiology; Ion channels;

D O I：

10.1007/BF01901509

中图分类号：

学科分类号：

摘要：

The electrophysiological properties of detrusor smooth muscle are described, in particular with regard to their influence on the contractile properties of the tissue. The Ca2+ and K+ channel activities are most important in generating action potentials, but the role of several other ionic currents is described, including Cl-, Ca2+-activated, stretch-activated and ligand-gated channels. The variable appearance and functions of different ionic currents in disease states is discussed, as well as the question of whether electrical activity can transmit between adjacent smooth muscle cells. In addition, the precise role that electrophysiological phenomena play in the regulation of the contractile state of the smooth muscle cells, as well as the generation of bladder electromyograms, is discussed.

引用

页码：291 / 298

页数：7

共 62 条

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