Angiogenesis antagonists: current clinical trials

被引：14

作者：

Steven Brem

机构：

[1] H. Lee Moffitt Cancer Center,Neuro

[2] University of South Florida,oncology Program

来源：

Angiogenesis | 1998年 / 2卷 / 1期

关键词：

Public Health; Clinical Trial; National Cancer Institute; Drug Development; Initial Experience;

D O I：

10.1023/A:1009068807898

中图分类号：

学科分类号：

摘要：

The Third Annual Cambridge Healthtech Institute symposium, entitled ‘Angiogenesis Antagonists: Current Clinical Trials, Drug Development and Regulatory Issues’, co-sponsored by the journal Angiogenesis and the Angiogenesis Foundation, convened on October 19 and 20 in Bermuda. The meeting attracted international experts from academia, the biopharmaceutical industry and the National Cancer Institute to share initial experiences in clinical trials of therapeutic modulation of angiogenesis. As molecular inhibitors move rapidly from the laboratory to the clinic, practical strategies were advanced to accelerate the introduction of the emerging class of pharmacological agents—angiogenesis antagonists. Themes of the meeting included:

引用

页码：9 / 20

页数：11

共 131 条

[1]

Folkman J.(1995)Angiogenesis in cancer, vascular, rheumatoid and other disease Nat Med 1 27-31

[2]

Folkman J.(1997)Angiogenesis inhibitors: from laboratory to clinic Cancer Invest 16 14-15

[3]

Folkman J.(1995)Clinical applications of research on angiogenesis N Engl J Med 333 1757-1763

[4]

Casey R(1997)Factors controlling ocular angiogenesis Am J Ophthalmol 124 521-529

[5]

Li W.(1996)Arterial gene therapy Lancet 348 1381-1020

[6]

Li WW(1996)Cyclosporine and angiogenesis in psoriasis J Am Acad Dermatol 35 1019-4085

[7]

Li VW(1997)Angiogenesis for revascularization of ischaemic tissues Eur Heart J 18 1—2-978

[8]

Casey R(1994)Thalidomide is an inhibitor of angiogenesis Proc Natl Acad Sci USA 91 4082-372

[9]

Tsakayannnis D.(1997)Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization Exp Eye Res 64 971-553

[10]

Li VW(1997)Phase I study of the antineovascularization drug CM101 Clin Cancer Res 3 365-35

← 1 2 3 4 5 6 7 8 9 10 →