Toxicity screening of materials from buildings with fungal indoor air quality problems (Stachybotrys chartarum)

被引：13

作者：

Johanning E. ^{[1
]}

Gareis M. ^{[2
]}

Yang C.S. ^{[3
]}

Hintikka E.-L. ^{[4
]}

Nikulin M. ^{[4
]}

Jarvis B. ^{[5
]}

Dietrich R. ^{[6
]}

机构：

[1] Mount Sinai School of Medicine, Dep. Community Medicine, Eastern New York Occupational and Environmental Health Center, Albany, NY

[2] Institute for Microbiology and Toxicology, Federal Meat Research Institute, Kulmbach

[3] P and K Microbiology, Cherry Hill, NJ

[4] National Veterinary and Food Research Institute, Helsinki

[5] Dep Chemistry and Biochemistry, University of Maryland, College Park, MD

[6] Institute for Hygiene and Technology of Food of Animal Origin, Veterinary Faculty, University of Munich, Munich

来源：

Mycotoxin Research | 1998年 / 14卷 / 2期

关键词：

Natural Killer Cell; Trichothecene; Mycotoxin Research; Gypsum Board; Trichothecene Mycotoxin;

D O I：

10.1007/BF02945095

中图分类号：

学科分类号：

摘要：

Samples of building materials visibly contaminated with moisture-related fungi (drywall, fiberglass, wallpaper, wood) were tested with indirect (FFL) and direct (MTT) cytotoxicity screening tests that are particularly sensitive to Stachybotrys chartarum toxins. In addition, microscopic, chemical, immunochemical (Roridin A enzyme immunoassay) and mycological culture analyses were performed. In all cases in which building occupants had reported verifiable skin, mucous membrane, respiratory, central nervous system or neuropsychological abnormalities, cytotoxicity was identified. Results of a cytotoxicity screening test of field samples, such as the direct MTT test method, will give investigators of health problems related to indoor air quality problems important toxicity information.

引用

页码：60 / 73

页数：13

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