Antitermite Activities of Coumarin Derivatives and Scopoletin from Protium javanicum Burm. f.

被引：27

作者：

Morina Adfa

Tsuyoshi Yoshimura

Kenichi Komura

Mamoru Koketsu

机构：

[1] Gifu University,Department of Materials Science and Technology, Faculty of Engineering

[2] Kyoto University,Research Institute for Sustainable Humanosphere (RISH)

[3] Bengkulu University,Department of Chemistry

来源：

Journal of Chemical Ecology | 2010年 / 36卷

关键词：

Burm. f.; Shiraki; Scopoletin; 6-Methoxycoumarin; 6-Hydroxycoumarin; Umbelliferone; SAR;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The antitermite (termiticidal and antifeedant) activity of Protium javanicum Burm. f. extract was investigated. The ethyl acetate fraction was active. Scopoletin (1), quercetin, and stigmasterol were isolated by bioassay-guided fractionation. Scopoletin had the highest activity among the three compounds. In order to investigate the structure-activity relationship (SAR) of the methoxy and hydroxy groups at the C-6 and C-7 positions of the coumarin skeleton, we synthesized several coumarin derivatives whose chemical structures are similar to scopoletin. Scopoletin exhibited the strongest termiticidal activity among the 10 compounds tested, followed by 6-methoxycoumarin (3), 6-hydroxycoumarin (7), and umbelliferone (8). All compounds except coumarin (9) showed antifeedant activity.

引用

页码：720 / 726

页数：6

共 138 条

[1]

Afek U(1986)6, 7-Dimethoxycoumarin, a citrus phytoalexin conferring resistance against Phytophthora gummosis Phytochemistry 25 1855-1856

[2]

Sztejnberg A(1987)Sterol of the Cucurbitaceae Phytochemistry 26 1693-1700

[3]

Carmely S(2002)Coumarins, coumarinoligninoids and terpenes from Biochem. Syst. Ecol. 30 685-687

[4]

Akihisa T(1986)Further flavonol glycosides from Phytochemistry 25 2361-2365

[5]

Shimizu N(1986)3-Methoxyflavones and coumarins from Phytochemistry 25 2357-2360

[6]

Ghosh P(1978)Termiticidal components of wood extracts: 7-methyljuglone from J. Agric. Food Chem. 26 869-873

[7]

Thakur S(2002)Antitermitic activity of leaf essential oils and components from J. Agric. Food Chem. 50 1389-1392

[8]

Rosenstein FU(2007)Anti-termitic activities of essential oils from coniferous trees against Bioresour. Technol. 98 456-459

[9]

Tamura T(1962)New syntheses in the coumarin series J. Org. Chem. 27 3083-3085

[10]

Matsumoto T(1998)Two 6, 7-dioxygenated coumarins from Pterocaulon virgatum Phytochemistry 48 707-710

← 1 2 3 4 5 6 7 8 9 10 →