Does lethal myocardial reperfusion injury exist?

Zweier J.L., Flaherty J.T., Weisfeldt M.L., Direct measurement of free radical generation following reperfusion of ischemic myocardium, Proc Natl Acad Sci USA, 84, pp. 1404-1407, (1987)

Grill H.P., Zweier J.L., Kuppusamy P., Weisfeldt M.L., Flaherty J.T., Direct measurement of myocardial free radical gen-eration in an in-vivo model: Effects of post-ischemic reperfusion and treatment with human recombinant superoxide dismutase, J Am Coll Cardiol, 20, pp. 1604-1611, (1992)

Ambrosio G., Weisfeldt M.L., Jacobus W.E., Flaherty J.T., Evidence of a reversible oxygen radical mediated component of reperfusion injury: Reduction by recombinant human superoxide dismutase administered at the time of reflow, Circulation, 75, pp. 282-291, (1987)

Zweier J.L., Rayburn B.K., Flaherty J.T., Weisfeldt M.L., Recombinant superoxide dismutase reduces oxygen free radical concentrations in reperfused myocardium, J Clin Invest, 80, pp. 1728-1734, (1987)

Ambrosio G., Becker L.C., Hutchins G.M., Weisman H.F., Weisfeldt M.L., Reduction in experimental infarct size by recombinant human superoxide dismutase: Insights into the pathophysiology of reperfusion injury, Circulation, 74, pp. 1424-1433, (1986)

Xia Y., Zweier J.L., Substrate control of free radical generation from xanthine oxidase in the postischemic heart, J Biol Chem, 270, pp. 18797-18803, (1995)

Flaherty J.T., Pitt B., Gruber J.W., Et al., Recombinant human superoxide dismutase (h-SOD) fails to improve recovery of ventricular function in patients undergoing coronary angioplasty for acute myocardial infarction, Circulation, 89, pp. 1982-1991, (1994)

Murohara Y., Yui Y., Hattori R., Kawai C., Effects of superoxide dismutase on reperfusion arrhythmias and left ventricular function in patients undergoing thrombolysis for anterior wall acute myocardial infarction, Am J Cardiol, 67, pp. 765-767, (1991)

Omar B.A., McCord J.M., Interstitial equilibration of superoxide dismutase correlates with its protective effect in the isolated rabbit heart, J Mol Cell Cardiol, 23, pp. 149-159, (1991)

Chi L., Tamura Y., Hoff P., Macha M., Gallagher K.P., Schork M.A., Lucchesi B.R., Effect of superoxide dismutase on myocardial infarct size in the canine heart after 6 hours of regional ischemia and reperfusion: A demonstration of myocardial salvage, Circ Res, 64, pp. 665-675, (1989)

Zweier J.L., Flaherty J.T., Weisfeldt M.L., Direct measurement of free radical generation following reperfusion of ischemic myocardium, Proc Natl Acad Sci USA, 84, pp. 1404-1407, (1987)

Grill H.P., Zweier J.L., Kuppusamy P., Weisfeldt M.L., Flaherty J.T., Direct measurement of myocardial free radical gen-eration in an in-vivo model: Effects of post-ischemic reperfusion and treatment with human recombinant superoxide dismutase, J Am Coll Cardiol, 20, pp. 1604-1611, (1992)

Ambrosio G., Weisfeldt M.L., Jacobus W.E., Flaherty J.T., Evidence of a reversible oxygen radical mediated component of reperfusion injury: Reduction by recombinant human superoxide dismutase administered at the time of reflow, Circulation, 75, pp. 282-291, (1987)

Zweier J.L., Rayburn B.K., Flaherty J.T., Weisfeldt M.L., Recombinant superoxide dismutase reduces oxygen free radical concentrations in reperfused myocardium, J Clin Invest, 80, pp. 1728-1734, (1987)

Ambrosio G., Becker L.C., Hutchins G.M., Weisman H.F., Weisfeldt M.L., Reduction in experimental infarct size by recombinant human superoxide dismutase: Insights into the pathophysiology of reperfusion injury, Circulation, 74, pp. 1424-1433, (1986)

Xia Y., Zweier J.L., Substrate control of free radical generation from xanthine oxidase in the postischemic heart, J Biol Chem, 270, pp. 18797-18803, (1995)

Flaherty J.T., Pitt B., Gruber J.W., Et al., Recombinant human superoxide dismutase (h-SOD) fails to improve recovery of ventricular function in patients undergoing coronary angioplasty for acute myocardial infarction, Circulation, 89, pp. 1982-1991, (1994)

Murohara Y., Yui Y., Hattori R., Kawai C., Effects of superoxide dismutase on reperfusion arrhythmias and left ventricular function in patients undergoing thrombolysis for anterior wall acute myocardial infarction, Am J Cardiol, 67, pp. 765-767, (1991)

Omar B.A., McCord J.M., Interstitial equilibration of superoxide dismutase correlates with its protective effect in the isolated rabbit heart, J Mol Cell Cardiol, 23, pp. 149-159, (1991)

Chi L., Tamura Y., Hoff P., Macha M., Gallagher K.P., Schork M.A., Lucchesi B.R., Effect of superoxide dismutase on myocardial infarct size in the canine heart after 6 hours of regional ischemia and reperfusion: A demonstration of myocardial salvage, Circ Res, 64, pp. 665-675, (1989)