Microfluidics in biotechnology

被引：62

作者：

Barry R. ^{[1
]}

Ivanov D. ^{[2
]}

机构：

[1] School of Biol. Sci. Royal Holloway, University of London, Egham

[2] Lab. de Physique des Polymeres, Université Libre de Bruxelles

来源：

Journal of Nanobiotechnology | / 2卷 / 1期

关键词：

Microfluidic Chip; Microfluidics Channel; Microfluidic System; Microfluidic Technology; Hybridisation Time;

D O I：

10.1186/1477-3155-2-2

中图分类号：

学科分类号：

摘要：

Microfluidics enables biotechnological processes to proceed on a scale (microns) at which physical processes such as osmotic movement, electrophoretic-motility and surface interactions become enhanced. At the microscale sample volumes and assay times are reduced, and procedural costs are lowered. The versatility of microfluidic devices allows interfacing with current methods and technologies. Microfluidics has been applied to DNA analysis methods and shown to accelerate DNA microarray assay hybridisation times. The linking of microfluidics to protein analysis techologies, e.g. mass spectrometry, enables picomole amounts of peptide to be analysed within a controlled micro-environment. The flexibility of microfluidics will facilitate its exploitation in assay development across multiple biotechnological disciplines. © 2004 Barry and Ivanov; licensee BioMed Central Ltd.

引用

页数：5

共 18 条

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