An elemental correlation study in cancerous breast tissue by total reflection x-ray fluorescence

被引:9
作者
Urszula Majewska
Janusz Braziewicz
Dariusz BanaŚ
Aldona Kubala-KukuŚ
Stanisław Góźdź
Marek Pajek
Jolanta Smok
Antoinette CJrbaniak
机构
[1] Holy cross Cancer Center,Institute of Physics
[2] Pedagogical University,undefined
来源
Biological Trace Element Research | 1997年 / 60卷
关键词
TRXRF; PIXE; XRF; NAA;
D O I
暂无
中图分类号
学科分类号
摘要
The total reflection x-ray fluorescence method (TRXRF) has been employed to determine of P, S, K, Ca, Cr, Mn, Fe, Ni, Cu, Zn, Se, Rb, Sr, and Pb concentration in the benign breast tumor tissue from 68 women and in the cancerous breast tissue from 26 women. Concentrations of most of elements show enhancement in cancerous breast tissue. Examined elements compete for binding sites in the cell, change its enzymatic activity, and exert direct or indirect action on the carcinogenic process accelerating the growth of rumors. Inhibition of enzymatic activity caused by variation in trace element concentrations results in immunological breakdown of the body system. An attempt has been made to correlate measured trace element concentrations with the clinical stage of cancer. Physical bases of used analytical method, experimental setup, and the procedure of sample preparation are described.
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页码:91 / 100
页数:9
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