The evolving role of partial nephrectomy in the management of renal cell carcinoma

被引:28
作者
Scott M. Gilbert
Paul Russo
Mitchell C. Benson
Carl A. Olsson
James M. McKiernan
机构
[1] Department of Urology, Columbia-Presbyterian Medical Center, New York, NY 10032
关键词
Renal Cell Carcinoma; Renal Tumor; Partial Nephrectomy; Radical Nephrectomy; Solitary Kidney;
D O I
10.1007/s11912-003-0116-5
中图分类号
学科分类号
摘要
The surgical management of renal cell carcinoma has undergone critical review over the past decade. Initially treated with radical nephrectomy, renal cell carcinoma is now approached with nephron-sparing surgical techniques. Improved imaging modalities have substantially increased the number of incidental renal tumors detected, and with the increasing number of incidentally detected kidney tumors, a size and stage migration has occurred in renal cell carcinoma. Early studies showed that disease-free survival rates were similar between cancers treated with radical and partial nephrectomy. The standard now is to offer partial nephrectomy as a surgical option to all patients with renal lesions measuring 4.0 cm or smaller in the setting of a normal contralateral kidney. More recent issues regarding partial nephrectomy concern complication rates and management, renal cell carcinoma multifocality, margin status and distance to normal renal parenchyma, cost analysis, and the development of laparoscopic techniques that duplicate open partial nephrectomy. The purpose of this review is to outline and analyze these more recent concerns regarding partial nephrectomy. Copyright © 2003 by Current Science Inc.
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收藏
页码:239 / 244
页数:5
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