Myocardial perfusion imaging by magnetic resonance imaging

被引:8
作者
Katherine C. Wu
机构
[1] Johns Hopkins Medical Institutions, Division of Cardiology, Baltimore, MD 21287
关键词
Single Photon Emission Compute Tomography; Myocardial Perfusion; Myocardial Perfusion Imaging; Left Anterior Descend; Dipyridamole;
D O I
10.1007/s11886-003-0039-7
中图分类号
学科分类号
摘要
In the diagnosis and treatment of patients with suspected or known coronary artery disease, noninvasive methodologies for assessing myocardial perfusion have been invaluable. Clinically, nuclear techniques such as single photon emission tomography thallium and sestamibi have predominated. They are limited, however, by the radiation burden, relatively poor spatial resolution, and attenuation artifact caused by soft tissue. In contrast, magnetic resonance imaging (MRI) is notable for its anatomic detail, sharp tissue contrast, excellent spatial and temporal resolution, versatility, and lack of ionizing radiation. It is therefore a potentially attractive alternative to nuclear imaging for the assessment of myocardial perfusion. This review summarizes the principles of MRI myocardial perfusion measurement, discusses recent clinical applications, and highlights future developments in the field. Copyright © 2003 by Current Science Inc.
引用
收藏
页码:63 / 68
页数:5
相关论文
共 37 条
[1]  
2002 Heart and Stroke Statistical Update, (2001)
[2]  
Manning W.J., Atkinson D.J., Grossman W., Et al., First-pass nuclear magnetic resonance imaging studies using gadolinium- DTPA in patients with coronary artery disease, J. Am. Coll. Cardiol., 18, pp. 959-965, (1991)
[3]  
Atkinson D.J., Burstein D., Edelman R.R., First-pass cardiac perfusion: Evaluation with ultrafast MR imaging, Radiology, 174, pp. 757-762, (1990)
[4]  
Strich G., Hagan P.L., Gerber K.H., Et al., Tissue distribution and magnetic resonance spin lattice relaxation effects of gadolinium-DTPA, Radiology, 154, pp. 723-726, (1985)
[5]  
Engtelstad B.L., Wolf G.L., Contrast agents, Magnetic Resonance Imaging, pp. 161-181, (1988)
[6]  
Schmiedl U., Ogan M.D., Moseley M.E., Et al., Comparison of the contrast-enhancing properties of albumin-(Gd-DTPA) and Gd-DTPA at 2.0 T: And experimental study in rats, AJR Am. J. Roentgenol., 147, pp. 1263-1270, (1986)
[7]  
Wilke N., Simm C., Zhang J., Et al., Contrast-enhanced first pass myocardial perfusion imaging: Correlation between myocardial blood flow in dogs at rest and during hyperemia, Magn. Reson. Med., 29, pp. 485-497, (1993)
[8]  
Bache R.J., Cobb F.R., Greenfield Jr. J.C., Myocardial blood flow distribution during ischemia-induced coronary vasodilation in the unanesthetized dog, J. Clin. Invest., 54, pp. 1462-1472, (1974)
[9]  
Diesbourg L.D., Prato F.S., Wisenberg G., Et al., Quantification of myocardial blood flow and extracellular volumes using a bolus injection of Gd-DTPA: Kinetic modeling in canine ischemic disease, Magn. Reson. Med., 23, pp. 239-253, (1992)
[10]  
Jerosch-Herold M., Wilke N., MR first pass imaging: Quantitative assessment of transmural perfusion and collateral flow, Int. J. Card. Imaging, 13, pp. 205-218, (1997)