Self-reported treatment adherence in inflammatory bowel disease in Indian patients

被引：21

作者：

Bhatt J. ^{[1
]}

Patil S. ^{[1
]}

Joshi A. ^{[1
]}

Abraham P. ^{[1
]}

Desai D. ^{[1
]}

机构：

[1] Division of Gastroenterology, P D Hinduja National Hospital and Medical Research Center, Mahim

来源：

Indian Journal of Gastroenterology | 2009年 / 28卷 / 4期

关键词：

Crohn1s disease; Glucocorticoids; Immunosuppressive agents; Mesalamine; Ulcerative colitis;

D O I：

10.1007/s12664-009-0050-z

中图分类号：

学科分类号：

摘要：

Non-adherence to medical therapy is emerging as an important determinant of relapse in patients with inflammatory bowel disease (IBD). Aim To find the prevalence of and reasons for non-adherence to medical therapy in Indian patients with IBD and its correlation with disease outcome. Methods In this cross-sectional study, we checked for adherence to treatment in 127 patients with IBD (117 ulcerative colitis and 10 Crohn's disease) using a questionnaire that inquired into frequency of missed doses, causes for missed doses, and its relation to relapse of disease. Results Of the 127 patients (mean age 42.8 years; 68 women), 103 (81%) were non-adherent to treatment, defined as taking 80% or less of the dose advised. The reasons for non-adherence (not mutually exclusive) were: forgetfulness-98 patients (77%), felt better-18 (14.2%), high frequency of doses-13 (10.1%), no effect of medications-10 (7.87%), non-availability of medications-3 (2.3%). Non-adherent patients were three times more likely to develop a relapse as compared to those with adherence (OR 3.389, 95% CI 1.29-8.88, p=0.012). Conclusions Over 80% of patients with IBD in this survey were non-adherent to medical treatment; forgetfulness was mentioned as the most common cause. Non-adherent patients were more likely to relapse. Patients need to be educated regarding the need for adherence to treatment in IBD. © Indian Society of Gastroenterology 2009.

引用

页码：143 / 146

页数：3

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