Genetic predictors of plasma lipid response to diet intervention

被引：8

作者：

Ordovas J.M. ^{[1
]}

Galluzzi J.R. ^{[1
]}

机构：

[1] Lipid Metabolism Laboratory, JM-USDA-Human Nutrition Research Center on Aging at Tufts University, Boston, MA

来源：

Current Atherosclerosis Reports | 1999年 / 1卷 / 3期

关键词：

Arterioscler Thromb Vasc Biol; Cholesterol Ester Transfer Protein; Fatty Acid Binding; Postprandial Lipemia; Retinyl Palmitate;

D O I：

10.1007/s11883-999-0032-8

中图分类号：

学科分类号：

摘要：

There is a growing interest in determining the genetic predictors of plasma lipid response to diet intervention. Several candidate gene loci, namely, apolipoprotein (APO) A1, APOA4, APOC3, APOB, APOE, CETP, LPL, and FABP2, have been shown to explain a significant, but still rather small, proportion of the interindividual variability in dietary response. Other gene loci code for products that play a relevant role in lipoprotein metabolism and are prime candidates for future studies (ie, CYP7). Future progress in this complex area will come from experiments carried out using animal models and from carefully controlled dietary protocols in humans. © 1999, Current Science Inc.

引用

页码：196 / 203

页数：7

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