Primary intracranial stenting in acute ischemic stroke

被引:6
作者
Velat G.J. [1 ]
Hoh B.L. [1 ]
Levy E.I. [2 ,3 ]
Mocco J. [1 ]
机构
[1] Department of Neurological Surgery, McKnight Brain Institute, University of Florida, Gainesville, FL 32610
[2] Departments of Neurosurgery and Radiology, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY
[3] Department of Neurosurgery, Millard Fillmore Gates Hospital, Kaleida Health, Buffalo, NY
关键词
Ischemic; Recanalization; Stenting; Stroke; Thrombolysis;
D O I
10.1007/s11886-009-0069-x
中图分类号
学科分类号
摘要
Acute intracranial stroke is a major source of morbidity and mortality in the United States. Recent studies have shown improved clinical outcomes for patients who achieve timely arterial recanalization. Multimodal therapies have evolved to meet this end point and include intravenous and/or intra-arterial thrombolysis and mechanical thrombolysis. Modifications to existing balloon-mounted stents commonly used in cardiology have yielded more easily navigable and safer self-expanding intracranial stents that provide rapid arterial recanalization. We review the evolution of acute stroke therapy over the past few decades and the recent results of mechanical thrombolysis, focusing on intracranial stenting in the setting of acute stroke. © 2009 Springer Science+Business Media, LLC.
引用
收藏
页码:14 / 19
页数:5
相关论文
共 32 条
  • [1] Lloyd-Jones D., Adams R., Carnethon M., Et al., Heart disease and stroke statistics-2009 update: A report from the American heart association statistics committee and stroke statistics subcommittee, Circulation, 119, pp. 480-486, (2009)
  • [2] Gobin Y.P., Starkman S., Duckwiler G.R., Grobelny T., Kidwell C.S., Jahan R., Pile-Spellman J., Segal A., Vinuela F., Saver J.L., MERCI 1: A phase 1 study of mechanical embolus removal in cerebral ischemia, Stroke, 35, 12, pp. 2848-2853, (2004)
  • [3] Hacke W., Kaste M., Bluhmki E., Et al., Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke, N Engl J Med, 359, pp. 1317-1329, (2008)
  • [4] Hacke W., Kaste M., Fieschi C., Et al., Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. the European cooperative acute stroke study (ECASS), JAMA, 274, pp. 1017-1025, (1995)
  • [5] Hacke W., Kaste M., Fieschi C., Von Kummer R., Davalos A., Meier D., Larrue V., Bluhmki E., Davis S., Donnan G., Schneider D., Diez-Tejedor E., Trouillas P., Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II), Lancet, 352, 9136, pp. 1245-1251, (1998)
  • [6] Rha J.-H., Saver J.L., The impact of recanalization on ischemic stroke outcome: A meta-analysis, Stroke, 38, 3, pp. 967-973, (2007)
  • [7] Smith W.S., Sung G., Starkman S., Saver J.L., Kidwell C.S., Gobin Y.P., Lutsep H.L., Nesbit G.M., Grobelny T., Rymer M.M., Silverman I.E., Higashida R.T., Budzik R.F., Marks M.P., Safety and efficacy of mechanical embolectomy in acute ischemic stroke: Results of the MERCI trial, Stroke, 36, 7, pp. 1432-1438, (2005)
  • [8] Zaidat O.O., Suarez J.I., Sunshine J.L., Et al., Thrombolytic therapy of acute ischemic stroke: Correlation of angiographic recanalization with clinical outcome, AJNR Am J Neuroradiol, 26, pp. 880-884, (2005)
  • [9] Barber P.A., Zhang J., Demchuk A.M., Et al., Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility, Neurology, 56, pp. 1015-1020, (2001)
  • [10] Tissue plasminogen activator for acute ischemic stroke, N Engl J Med, 333, pp. 1581-1587, (1995)