Use of radionuclide imaging in acute coronary syndromes

被引：4

作者：

Brian G. Abbott

Frans J. Wackers

机构：

[1] Yale University School of Medicine, VA Connecticut Healthcare System, West Haven, CT 06516

来源：

Current Cardiology Reports | 2003年 / 5卷 / 1期

关键词：

Single Photon Emission Compute Tomography; Acute Coronary Syndrome; Infarct Size; Myocardial Perfusion Imaging; Nuclear Cardiology;

D O I：

10.1007/s11886-003-0034-z

中图分类号：

学科分类号：

摘要：

The triage of patients presenting to the emergency department (ED) with acute chest pain is a diagnostic challenge. Radionuclide myocardial perfusion imaging has been shown to have favorable diagnostic and prognostic value in this setting, with an excellent early sensitivity to detect acute myocardial infarction (MI) not achieved by other testing modalities. A normal resting perfusion imaging study has been shown to have a negative predictive value of over 99% to exclude MI. Observational and randomized trials of both rest and stress imaging in the ED evaluation of patients with chest pain have demonstrated reductions in unnecessary hospitalizations and cost savings compared with routine care. Perfusion imaging has also been used in risk stratification after MI, and for measurement of infarct size to evaluate reperfusion therapies. Novel hot spot" imaging radiopharmaceuticals that visualize infarction or ischemia are currently undergoing evaluation and hold promise for future imaging of acute coronary syndromes. Copyright © 2003 by Current Science Inc."

引用

页码：25 / 31

页数：6

共 36 条

[1]

Duca M.D., Giri S., Wu A.H., Et al., Comparison of acute rest myocardial perfusion imaging and serum markers of myocardial injury in patients with chest pain syndromes, J. Nucl. Cardiol., 6, pp. 570-576, (1999)

[2]

Hilton T.C., Fulmer H., Abuan T., Et al., Ninety-day follow-up of patients in the emergency department with chest pain who undergo initial single-photon emission computed tomographic perfusion scintigraphy with technetium 99m-labeled sestamibi, J. Nucl. Cardiol., 3, pp. 308-311, (1996)

[3]

Kontos M.C., Jesse R.L., Anderson F.F., Et al., Comparison of myocardial perfusion imaging and cardiac troponin I in patients admitted to the emergency department with chest pain, Circulation, 99, pp. 2073-2078, (1999)

[4]

Radensky P.W., Hilton T.C., Fulmer H., Et al., Potential cost effectiveness of initial myocardial perfusion imaging for assessment of emergency department patients with chest pain, Am. J. Cardiol., 79, pp. 595-599, (1997)

[5]

Tatum J.L., Jesse R.L., Kontos M.C., Et al., Comprehensive strategy for the evaluation and triage of the chest pain patient, Ann. Emerg. Med., 29, pp. 116-125, (1997)

[6]

Weissman I.A., Dickinson C.Z., Dworkin H.J., Et al., Cost-effectiveness of myocardial perfusion imaging with SPECT in the emergency department evaluation of patients with unexplained chest pain, Radiology, 199, pp. 353-357, (1996)

[7]

Udelson J.E., Spiegler E.J., Emergency department perfusion imaging for suspected coronary artery disease: The ERASE chest pain trial, Maryland Med., SUPPL., pp. 90-94, (2001)

[8]

Stowers S.A., Eisenstein E.L., Wackers F.J., Et al., An economic analysis of an aggressive diagnostic strategy with single photom emission computed tomography myocardial perfusion imaging and early exercise stress testing in emergency department patients who present with chest pain but nondiagnostic electrocardiograms: Results from a randomized trial, Ann. Emerg. Med., 35, pp. 17-25, (2000)

[9]

Wackers F.J., Brown K.A., Heller G.V., Et al., American Society of Nuclear Cardiology position statement on radionuclide imaging in patients with suspected acute ischemic syndromes in the emergency department or chest pain center, J. Nucl. Cardiol., 9, pp. 246-250, (2002)

[10]

Abbott B.G., Abdel-Aziz I., Nagula S., Et al., Selective use of single-photon emission computed tomography myocardial perfusion imaging in a chest pain center, Am. J. Cardiol., 87, pp. 1351-1355, (2001)

← 1 2 3 4 →