Neurocircuitry of anxiety disorders

被引:75
作者
Justine M. Kent
Scott L. Rauch
机构
[1] Department of Psychiatry, Columbia University, New York, NY 10032
关键词
Anxiety Disorder; Social Phobia; Social Anxiety Disorder; Panic Disorder; Panic Disorder;
D O I
10.1007/s11920-003-0055-8
中图分类号
学科分类号
摘要
A major focus in the field of anxiety in the past decade, and an area of intense ongoing interest, is the delineation of the basic neurocircuitry underlying normal and pathologic anxiety. Preclinical work defining the basic neurocircuitry responsible for fear responding has fueled neuroimaging investigations attempting to model the neurocircuitry of the anxiety disorders. Herewith, the authors review neuroimaging findings contributing to the development and refinement of neuroanatomic models for post-traumatic stress disorder, panic disorder, and social anxiety disorder. Copyright © 2003 by Current Science Inc.
引用
收藏
页码:266 / 273
页数:7
相关论文
共 69 条
[1]  
Davis M., The role of the amygdala in fear and anxiety, Ann. Rev. Neurosci., 58, SUPPL., pp. 26-28, (1992)
[2]  
LeDoux J.E., Iwata J., Cicchetti P., Et al., Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of conditioned fear, J. Neurosci., 8, pp. 2517-2519, (1988)
[3]  
Rauch S.L., Whalen P.J., Curran T., Et al., Probing striato-thalamic function in OCD and TS using neuroimaging methods, Tourette Syndrome, (2000)
[4]  
Fyer A.J., Current approaches to etiology and pathophysiology of specific phobia, Biol. Psychiatry, 44, pp. 1295-1304, (1998)
[5]  
Rauch S.L., Neuroimaging and the neurobiology of anxiety disorders, Handbook of Affective Sciences, pp. 963-975, (2003)
[6]  
LeDoux J.E., Cicchetti P., Xagoraris A., Et al., The lateral amygdaloid nucleus: Sensory interface of the amygdala in fear conditioning, J. Neurosci., 10, pp. 1062-1069, (1990)
[7]  
Aggleton J.P., The Amygdala: Neurobiological Aspects of Emotion, Memory and Mental Dysfunction, (1992)
[8]  
LeDoux J.E., The Emotional Brain, (1996)
[9]  
Jones D.K., Simmons A., Williams S.C., Horsfield M.A., Non-invasive assessment of axonal fiber connectivity in the human brain via diffusion tensor MRI, Magn. Reson. Med., 42, pp. 37-41, (1999)
[10]  
Sato T., Hasan K., Alexander A.L., Minato K., Structural connectivity in white matter using the projected diffusion-tensor distance, Medinfo., 10, pp. 929-932, (2001)