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The natural history of multiple sclerosis
被引：6
作者：
G.C. Ebers
机构：
[1] Department of Clinical Neurology,
[2] Radcliff Infirmary,undefined
[3] University of Oxford,undefined
[4] Woodstock Road,undefined
[5] Oxford,undefined
[6] OX2 6HE,undefined
[7] UK,undefined
关键词：
Clinical Trial;
Multiple Sclerosis;
Chronic Disease;
Natural History;
Generation Clinical Trial;
D O I：
10.1007/s100720070018
中图分类号：
学科分类号：
摘要：
The natural history of chronic diseases is generally poorly understood. Multiple sclerosis os one of the best-studied diseases and we outline here some of the information obtained from 25 000 patient-years of observation. This population-based cohort received almost no treatment and certainly none known to alter the long-term natural course of the illness. There is a possibility that such data will prove useful in new generation clinical trials which are observational in nature.
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页码：S815 / S817
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