Diabetic diarrhea

被引:31
作者
Gould M. [1 ]
Sellin J.H. [1 ]
机构
[1] Section of Gastroenterology, Baylor College of Medicine, Houston, TX 77030
关键词
Metformin; Chronic Pancreatitis; Celiac Disease; Fecal Incontinence; Exenatide;
D O I
10.1007/s11894-009-0054-y
中图分类号
学科分类号
摘要
Diabetic patients with diarrhea may present clinical challenges in diagnosis and treatment. Particular diagnoses are more prevalent in diabetic patients than in the general population. Medications are often a culprit for chronic diarrhea, and the medication list should always be carefully scrutinized for those with diarrhea as a side effect. In diabetic patients, metformin is a common cause of diarrhea. Diabetic patients are more likely to have associated diseases (eg, celiac sprue and microscopic colitis) that present with diarrhea as the sole complaint. Ingested sugar-free foods that may contain sorbitol or other agents can cause diarrhea in diabetic patients. Finally, diabetic enteropathy can itself cause diarrhea. The various etiologies can be diagnosed with a thorough history and appropriate diagnostic tests. This article focuses on the etiologies of diarrhea that are seen with higher incidence in diabetic patients. © Current Medicine Group, LLC 2009.
引用
收藏
页码:354 / 359
页数:5
相关论文
共 50 条
[1]
Bytzer P., Talley N.J., Leemon M., Et al., Prevalence of gastrointestinal symptoms associated with diabetes mellitus, Arch Intern Med, 161, pp. 1989-1996, (2001)
[2]
Vinik A., Erbas T., Recognizing and treating diabetic autonomic neuropathy, Cleve Clin J Med, 68, pp. 934-944, (2001)
[3]
Lysy J., Israeli E., Goldin E., The prevalence of chronic diarrhea among diabetic patients, Am J Gastroenterol, 94, pp. 2165-2170, (1999)
[4]
Berchtold P., Dahlqvist A., Gustafson A., Et al., Effects of a biguanide (Metformin) on vitamin B12 and folic acid absorption and intestinal enzyme activities, Scand J Gastroenterol, 6, pp. 751-754, (1971)
[5]
Bytzer P., Talley N.J., Jones M.P., Et al., Oral hypoglycaemic drugs and gastrointestinal symptoms in diabetes mellitus, Aliment Pharmacol Ther, 15, pp. 137-142, (2001)
[6]
Foss M.T., Clement K.D., Metformin as a cause of late-onset chronic diarrhea, Pharmacotherapy, 21, pp. 1422-1424, (2001)
[7]
Ratnaike R.N., Jones T.E., Mechanisms of drug-induced diarrhoea in the elderly, Drugs Aging, 13, pp. 245-253, (1998)
[8]
Byetta, (2008)
[9]
Jacob S., Rabbia M., Meier M.K., Et al., Orlistat 120 mg improves glycaemic control in type 2 diabetic patients with or without concurrent weight loss, Diabetes Obes Metab, 11, pp. 361-371, (2009)
[10]
Drent M.L., van der Veen E.A., Lipase inhibition: A novel concept in the treatment of obesity, Int J Obes Relat Metab Disord, 17, pp. 241-244, (1993)